4 Scientifically-Backed Anti-Aging Pills to Know About

Anti-aging pills that keep you healthy, no matter how old you get, seem like a myth.  After all, if there is one thing you know about getting old it’s this: you’re going to get sick.  Be it from heart disease, or cancer, or Alzheimer’s disease, or diabetes, or some other serious ailment, you’re sure that getting older means getting sicker.

Unfortunately, your belief about growing old isn’t unfounded.  Older people do fall ill more frequently than younger people.  In fact, the overwhelming majority of people suffer ill health in their later years and most ultimately die from their illness.

But, all of that may be about to change, thanks to science.

After decades of dedicated work, researchers are finally starting to piece together exactly how and why you become ill as you age.  And this clearer picture of aging is opening up the possibility, for the first time in history, of developing targeted treatments to prevent it.  We, finally, have the chance to create real-life (completely myth-less!) anti-aging pills.

Read: Tools to Life Long Wellness: Understanding How and Why You Age

In this article we will review the four leading candidates for anti-aging pills that researchers now think could help slow aging and keep you healthy as you grow older.

For each candidate, we will describe how it works in the body and explore the research that has bumped it to the top of the anti-aging hopefuls.

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4 Anti-Aging Pills That May Lengthen Healthy Lifespan

1. Rapamycin

What Is It?

Researchers first discovered rapamycin in a type of soil bacteria.  It was first interesting to scientists because it had antifungal properties.  With more research, though, scientists found that it also helped to suppress the immune system, slowed the spread of disease, regulated cell growth and influenced metabolism.  

Most recently, researchers discovered that rapamycin can also modulate aging and the development of age-related diseases.

The Evidence It Helps Lengthen Healthy Lifespan

Most studies testing the effectiveness of rapamycin for longevity have been done on mice. Many studies carried out from 2009 to 2011 caused ripples in the world of anti-aging research; they found that rapamycin, indeed, lengthened mice’s lives.  The question of whether it actually helped to slow aging (kept the mice healthy while they lived longer), however, remained unanswered.

Researchers published many studies over the next several years and had contradictory results.  

One study published in 2012 by researchers at the University of Michigan found that rapamycin did slow aging.  They found that rapamycin could slow liver damage and improve general cell health, uterine health, and the function of other organs.

Another study, however, found that rapamycin had limited anti-aging effects, and that these were probably related to its tumor-suppressing effects.  Similar results came from another study

So, while rapamycin appears to have some positive effects on aging in animal studies, it is too early in the research game for this pill to call it a miracle drug for humans.  Researchers are hopeful, though, that it might prove to be a powerful tool in our fight against age-related diseases!

Where Can You Get It?

Rapamycin, often known as Sirolimus, is an “anti-aging pill” not available over-the-counter.  Doctors must prescribe rapamycin to patients because it may also prove to have serious side effects, including an increased likelihood of cancer or serious infection.

2. Curcumin 

What Is It?

Curcuma longa, the plant from which turmeric is derived, has long been used in Asia as a medicinal herb and spice.  Researchers believe that curcumin, a component in the turmeric spice, is responsible for many of the health properties of the root.  Studies show that curcumin has anti-inflammatory, antioxidant, and cancer fighting properties.

The Evidence It Helps Lengthen Healthy Lifespan

Studies in Worms

One study examined the potential anti-aging effects of curcumin in C. elegans, which is the scientific name for a type of roundworm.  Researchers found that curcumin did, indeed increase lifespan, and reduced free radicals associated with cell aging in these worms.

Curcumin’s antioxidative properties were found to be responsible for fighting the free radicals, protecting the worm’s cells from damage and disease, and increasing their lifespan.  

Studies in Fruit Flies

A similar study was carried out with two different strains of fruit flies (Drosophila melanogaster) that were fed curcumin.  Researchers found that curcumin extended the life span of both strains of fruit flies.  And, like the group that studied the roundworms, these researchers also detected protection against free radicals and improved cell health.  

Interestingly, this study found that the flies who ate curcumin had differences in how their cells read their DNA.  Flies whose diets contained curcumin had fewer aging genes turned on than those that didn’t.  This means curcumin may be able to slow aging and age-related diseases right at the very root of cellular health.

Excitingly, these results could be confirmed by a second study!

Studies in Mice

A third group of studies were carried out with mice, which helped to determine that curcumin could influence the longevity of more complex animals.  

Curcumin was found to improve protect against free radicals, improve artery function (i.e. reduce the risk of heart disease), reduce the risk of Alzheimer’s disease and help mice with dysfunctions in brain circulation (i.e. reduce the risk of other dementias).

Studies in Humans

Unfortunately, there are no human clinical trials looking at aging and curcumin, yet.  

So far, we only have a few studies carried out on human skin cells.  Importantly, though, these studies matched the results from studies on animals.  They showed the same protection against free radicals we’d seen in animal cells.  

This doesn’t prove that curcumin can slow aging and disease in humans, for sure, but it does suggest it really could!

Where Can You Get It?

You can get curcumin in the form of some simple turmeric at your local grocery store.

If you’d like a more potent punch, though, you can buy pure curcumin supplement.  Here are a couple curcumin supplement brands we love!

Bio Schwartz Premium Ultra Pure Turmeric Curcumin With BioPerine

Bio Schwartz Turmeric Curcumin

This is a best-seller on Amazon.com, and boasts highest potency available.  It is natural and non-GMO, and contains a patented black-pepper formula (BioPerine) to boost absorption.  It has 4.5 stars based on almost 10,000 reviews and is super affordable!

Smarter Nutrition CurcuminSmarter Nutrition Curcumin

This curcumin supplement comes in softgel form, which may be easier for you to swallow. In addition to having high-potency curcumin, it also black cumin seed, ginger, and patented AstraGin, increasing absorbability to over 90%.

3. Green Tea/EGCG

What Is It?

EGCG is short for epigallocatechin gallate, which is a component in tea leaves.  It is found in green tea, white tea, and black tea, but found in much higher quantities in green tea than the other two.  EGCG is a type of antioxidant that is known for having special positive effects on heart and metabolic health.  

The Evidence It Helps Lengthen Healthy Lifespan

Unlike the previous two anti-aging pill candidates, researchers have tested EGCG (in the form of green tea, usually) in humans.

Studies have shown positive effects of 2-3 cups of green tea (containing about 200-300 mg EGCG per cup) on heart health, diabetesbrain health and longevity in humans.

Where Can You Get It?

You can pick up EGCG in the form of green tea or pick up a concentrated EGCG supplement.  Check out our favorite brands of each!

Prince of Peace 100% Organic Green Tea

Price of Peace Green Tea

If you prefer the green tea experience to supplements, we recommend Prince of Peace Organic Green Tea.  Each box contains 100 tea bags, at a very affordable price.  It is also certified organic, so you can be sure you aren’t drinking any nasty pesticides.

Nature’s Wellness Green Tea Extract

Nature;s EGCG Green Tea Extract Capsules

These high-potency ECGC capsules also contain other beneficial components found in green tea, like slow-releasing caffeine.  They have 4.5 stars on Amazon, and each affordable bottle provides 2 months of supplements.

4. SIRT1 Activators

What Are They?

Sirtuin type 1 (SIRT1, for short) is an enzyme found naturally in your body.  When activated SIRT1 has powerful antioxidative properties that help to protect against cellular damage and disease

SIRT1-activators are naturally-occurring compounds that do just what their name suggests: they activate SIRT1.  

The Evidence They Help Lengthen Healthy Lifespan

SIRT1 has been widely studied in animal models over the past several years.  The evidence shows that activated SIRT1 can improve cellular health, directly turn off cellular processes that cause aging and extend lifespan in animals. 

The data is so impressive that, even though we don’t have studies in humans yet, one group of researchers felt confident enough to write: “it is hard to deny the potential of Sirt1-activating compounds for the treatment of many diseases such as cancer and type-2 diabetes, thereby improving human health and life expectancy.”  

In other words, it is difficult to deny that SIRT1 activators will almost certainly be able to promote health and help fight aging in humans.

Where Can You Get Them?

SIRT1 activators are found naturally in foods with high antioxidant content (such as capers, lovage apple, tea, onions, citrus fruits, green vegetables, and berries).  You can also find them in some antioxidant-rich or anti-inflammatory supplements (such as DHA Omega-3 Fatty Acid capsules).

4 Scientifically-Backed Anti-Aging Pills To Know About

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Take Home Message

For all of human history, aging, and getting sick while we age, was an unavoidable part of life.  Thanks to recent breakthroughs in aging science, we now know that this may not be entirely true.  Rapamycin, curcumin, EGCG and SIRT1-activators are the leading serious candidates for our first ever anti-aging pills, and there is real scientific evidence that they may work.  Healthier aging may very well be on the horizon!

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